Tuesday, August 25, 2020

Assignment on Amlodipine free essay sample

Amlodipine (Norvasc (Pfizer) and generics) (as besylate, mesylate or maleate) is a long-acting calcium channel blocker (dihydropyridine (DHP) class) utilized as an enemy of hypertensive and in the treatment of angina. Like other calcium channel blockers, amlodipine acts by loosening up the smooth muscle in the blood vessel divider, diminishing complete fringe opposition and subsequently lessening pulse; in angina it builds blood stream to the heart muscle (in spite of the fact that DHP-class calcium channel blockers are more particular for corridors than myocardium, as the cardiovascular calcium channels are not of the dihydropyridine-type). Orderly (IUPAC) name (RS)- 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)- 6-methyl-1,4-dihydropyridine-3,5-dicarboxylate. Stereoisomerism Amlodipine is a chiral calcium foe, presently available and in restorative use as a racemate [1:1 blend of (R)- (+)- and (S)- (â€)- amlodipine]] A technique for the semi-preparative chromatographic decontamination of the enantiomers (S)- (â€)- amlodipine and (R)- (+)- amlodipine has been accounted for. Enantiomer of amlodipine DESCRIPTION NORVASC ® is the besylate salt of amlodipine, a long-acting calcium channel blocker. We will compose a custom article test on Task on Amlodipine or on the other hand any comparable point explicitly for you Don't WasteYour Time Recruit WRITER Just 13.90/page Amlodipine besylate is artificially depicted as 3-Ethyl-5-methyl ( ±)- 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)- 1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate, monobenzenesulphonate. Its observational recipe is C 20 H 25 CIN 2 O 5 †¢C 6 H 6 O 3 S, and its auxiliary equation is: Amlodipine besylate is a white crystalline powder with a sub-atomic load of 567. 1. It is marginally dissolvable in water and sparingly solvent in ethanol. NORVASC (amlodipine besylate) tablets are defined as white tablets equal to 2. 5, 5 and 10 mg of amlodipine for oral organization. In clinical examinations, most patients with coronary supply route infection required 10 mg. Regular Adult Amlodipine Dose for Coronary Artery Disease: Chronic stable or vasospastic angina, or angiographically recorded coronary corridor illness in patients without cardiovascular breakdown or a discharge part under 40%: 5 to 10 mg orally once every day Most patients with incessant stable or vasospastic angina require 10 mg for satisfactory impact. In clinical investigations, most patients with coronary course sickness required 10 mg. Normal Geriatric Amlodipine Dose for Hypertension: Initial portion: 2. 5 mg orally once per day Maintenance portion: 2. 5 to 10 mg orally once every day Normal Geriatric Dose for Angina Pectoris: Chronic stable or vasospastic angina: 5 to 10 mg orally once per day The lower portion is suggested in the old; be that as it may, most patients require 10 mg for sufficient impact. Normal Pediatric Dose for Hypertension: 6 to 17 years: 2. 5 mg to 5 mg orally once a day Doses more than 5 mg day by day have not been concentrated in pediatric patients. Significant data about amlodipine Before taking amlodipine, tell your primary care physician in the event that you have congestive cardiovascular breakdown or liver ailment. Drinking liquor can additionally bring down your pulse and may expand certain symptoms of amlodipine. In the event that you are being treated for hypertension, continue utilizing amlodipine regardless of whether you feel well. Hypertension frequently has no manifestations. You may need to utilize circulatory strain drug for an amazing remainder. Amlodipine is just piece of a total program of treatment that may likewise incorporate eating routine, work out, weight control, and different drugs. Follow your eating routine, medicine, and exercise schedules intently. Inform your primary care physician concerning all other heart or pulse drugs you are taking. Your chest torment may turn out to be more terrible when you first beginning taking amlodipine or when your portion is expanded. Call your primary care physician if your chest torment is serious or progressing. Before taking amlodipine You ought not take this drug on the off chance that you are adversely affected by amlodipine. To ensure you can securely take amlodipine, tell your primary care physician in the event that you have any of these different conditions: * a heart valve issue called aortic stenosis; * congestive cardiovascular breakdown; or * liver infection. On the off chance that you are likewise taking a beta-blocker medicate, (for example, Betapace, Blocadren, Corgard, Coreg, Inderal, InnoPran, Lopressor, Normodyne, Tenoretic, Tenormin, Toprol, Trandate, Zebeta, and others) don't out of nowhere quit utilizing the beta-blocker without first conversing with your primary care physician. You may need to utilize less and less before you stop the prescription totally. Halting a beta-blocker also rapidly can cause genuine heart issues that won't be forestalled by amlodipine. FDA pregnancy class C. It isn't known whether amlodipine will hurt an unborn infant. Tell your primary care physician on the off chance that you are pregnant or plan to get pregnant while utilizing this prescription. It isn't known whether amlodipine goes into bosom milk or in the event that it could hurt a nursing child. You ought not bosom feed while you are taking amlodipine. Amlodipine reactions Get crisis clinical assistance on the off chance that you have any of these indications of an unfavorably susceptible response to amlodipine: hives; trouble breathing; growing of your face, lips, tongue, or throat. Call your PCP on the double on the off chance that you have a genuine symptom, for example, * feeling like you may drop; * growing in your grasp, lower legs, or feet; * beating pulses or shuddering in your chest; or * chest agony or substantial inclination, torment spreading to the arm or shoulder, sickness, perspiring, general sick inclination. Less genuine amlodipine symptoms may include: * migraine;

Saturday, August 22, 2020

Genetic Ownership :: Genes Science DNA Essays

Hereditary Ownership In the previous century, headways in science and innovation have permitted man to additionally examine his cause. Science has exhibited every single living thing are comprised of cells and cells contain hereditary material. Researchers before long will have the option to take hereditary material from one gathering and make their qualities in another. In doing as such, people, researchers, and society will be confronted with new difficulties concerning the proprietorship privileges of hereditary material. The accompanying will inspect moral issues of hereditary possession by taking a gander at present and future utilizations of innovation and the moral difficulties they incite. In 1978 the study of generation detonated into open cognizance with the introduction of Louise Brown, the principal child conceived as a result of In Vitro Fertilization (IVF). Today utilizing IVF, a couple with richness issues can give their own hereditary material as sperm and eggs to a center, join them to make undeveloped organisms, and addition the incipient organisms into a mother’s belly. Society acknowledges a people option to give their own hereditary material to an IVF facility and make youngsters. Today IVF is a multibillion-dollar, universal business giving solid kids to caring guardians. In 1997 another blast of open cognizance happened when the Roslin Institute declared they had effectively cloned a sheep named Dolly. Dolly was not the result of sperm and eggs, rather she was a definite clone of her contributor parent. The incipient organism of Dolly was made from hereditary material of a giver parent and embedded into a substitute mother. Dolly and her contributor parent right now live as the property of the Roslin Institute in Edinburgh, UK. As proprietor of sheep, Roslin had the option to gather hereditary material, perform inquire about, and in the long run produce a cloned creature. Today this privilege of proprietorship is right now acknowledged by society. Later on, people may reserve the option to utilize their hereditary material to replicate imperative organs to be utilized as transplants for ailing, twisted, or harmed body parts. This procedure is called helpful cloning. Science has exhibited every single living thing are comprised of cells and all cells contain hereditary material. At the center of all hereditary material is an essential part of life, DNA. Basically, DNA (Deoxyribonucleic Acid) trains cells how to isolate and develop into the living things we see each day. Each human has one of a kind DNA. No two people DNA is actually indistinguishable except for indistinguishable twins.

Sunday, August 9, 2020

The Relationship Between PTSD and Psychosis

The Relationship Between PTSD and Psychosis PTSD Related Conditions Print The Relationship Between PTSD and Psychosis By Matthew Tull, PhD twitter Matthew Tull, PhD is a professor of psychology at the University of Toledo, specializing in post-traumatic stress disorder. Learn about our editorial policy Matthew Tull, PhD Medically reviewed by a board-certified physician Updated on August 15, 2019 Post-Traumatic Stress Disorder Overview Symptoms & Diagnosis Causes & Risk Factors Treatment Living With In Children Frank van Groen / LOOK-foto / Getty Images In This Article Table of Contents Expand Types of Psychotic Symptoms Mental Health Disorders With Psychosis Schizophrenia and PTSD Psychotic Symptoms in PTSD What This Means Treatment Is Critical View All Post-traumatic stress disorder (PTSD) and symptoms of psychosis, such as hallucinations, often occur together. In clinical terms, PTSD is described as consisting of four clusters of symptoms: re-experiencing symptoms, avoidance symptoms, negative changes in mood and brain function, and hyperarousal symptoms.?? However, some mental health professionals believe that the experience of psychotic symptoms should be considered as an addition to that list, given that they commonly occur among people with PTSD. Types of Psychotic Symptoms Psychotic symptoms can be divided into two groups: positive symptoms and negative symptoms. This doesnt mean that some psychotic symptoms are good and some are bad. Rather, positive symptoms refer to an experience, such as hallucinations, whereas negative symptoms refer to the lack of an experience. Positive Psychotic Symptoms Positive psychotic symptoms are characterized by the presence of unusual feelings, thoughts, or behaviors.?? This includes experiences such as hallucinations or delusions. Hallucinations refer to sensations of something that isnt really there. An auditory hallucination is an experience of hearing voices that arent there. A visual hallucination would involve seeing something that isnt real. Tactile hallucinations occur when you feel something that isnt there. Olfactory and gustatory hallucinations involve the experience of smelling or tasting something that isnt present.Delusions are ideas that you believe are true despite the fact that they may be unlikely or odd. For example, you might believe that the CIA is spying on you or that aliens are controlling your behaviors or thoughts.Disorganized behaviors are also very common with psychosis. You may, for example, make up words, speak in unintelligible ways, or stand in an odd pose. Positive Psychotic Symptoms Negative Psychotic Symptoms Negative psychotic symptoms are characterized by the absence of experience. For example, if you have negative symptoms, you may not be emotionally expressive. You may have difficulty speaking, may not say anything for days on end (called alogia) or be unable to accomplish simple tasks or activities, such as getting dressed in the morning.?? You may appear very unmotivated and withdrawn. Mental health professionals often refer to this lack of emotional expression as a person having a flat affect. Negative Psychotic Symptoms Flashbacks and Dissociation Flashbacks and dissociation occur commonly with PTSD, and though they are not psychotic symptoms, they share some features with psychosis, including: In a flashback, you may temporarily lose connection with your present situation, being transported back in time to a traumatic event in your memory. In a severe flashback, you may see, hear, or smell things that other people dont, consistent with a hallucination. Flashbacks often occur during periods of high stress and can be very frightening to the person experiencing them.Dissociation is an experience in which you feel disconnected from your body.?? You may not have any memory of whats happening in your environment for a period of time. The experience is similar to a daydream, but unlike a normal daydream, its very disruptive to your life. Flashbacks and Dissociation in PTSD Mental Health Disorders That Include Psychotic Symptoms These positive and negative psychotic symptoms may be seen with a number of different mental health disorders, including: PTSDBipolar disorderSchizophreniaMajor depressive disease with psychotic featuresSchizoaffective disorderSchizophreniform disorderDelusional disorder The distinction between these conditions is sometimes difficult, as there can be considerable overlap between different symptoms and conditions. Schizophrenia and PTSD Considering that schizophrenia is one of the most common psychiatric diagnoses, its not surprising that some people may have both schizophrenia and PTSD. PTSD most commonly occurs after a traumatic experience, and it has been found that traumatic experiences are more common for those with schizophrenia than for the general population. A recent study, in addition, found that there is significant genetic overlap between schizophrenia and PTSD.?? Treatment for both disorders is critical, yet some physicians are reluctant to use some of the normal approaches. For example, using exposure therapy for PTSD might not be the best choice when a person also has schizophrenia, since exposure therapy may worsen the symptoms of schizophrenia. That said, studies have found that well-thought-out treatment can reduce the symptoms of PTSD. For those who have this combination of conditions, its important to find a mental health provider who is familiar with the treatment of both conditions. Psychotic Symptoms in PTSD Researchers at the University of Manitoba, Columbia University, and the University of Regina examined the data on 5,877 people from across the United States in order to determine the rates with which people with PTSD experience different psychotic symptoms. They found that among people with PTSD, the experience of positive psychotic symptoms was most common.?? Approximately 52 percent of people who reported having PTSD at some point in their lifetime also reported experiencing a positive psychotic symptom. Most Common Psychotic Symptoms in PTSD The most common positive symptoms in the study above were:Believing that other people were spying on or following them (27.5 percent)Seeing something that others couldnt see (19.8 percent)Having unusual feelings inside or outside of their bodies, such as feeling as though they were being touched when no one was really there (16.8 percent)Believing that they could hear what someone else was thinking (12.4 percent)Being bothered by strange smells that no one else could smell (10.3 percent)Believing that their behaviors and thoughts were being controlled by some power or force (10 percent) Not surprisingly, it appears that the more PTSD symptoms youre experiencing, the greater the likelihood that you will also experience positive psychotic symptoms. Researchers have also looked at which  traumatic events are most commonly related to the experience of psychotic symptoms. The events that put people most at risk include being involved in a  natural disaster, seeing someone  injured or killed, or experiencing shock as a result of a traumatic event that happened to a loved one. What This Means The experience of psychotic symptoms may tell the story of just how severe a persons case of PTSD is and how well he or she is coping with the condition. It may also raise red flags about the likelihood of potentially dangerous behaviors. It has been suggested that the experience of psychotic symptoms in those with PTSD may be connected to the experience of dissociation described above. Frequent dissociation may increase the risk for the development of psychotic symptoms.?? Studies have shown that people with PTSD who experience psychotic symptoms, as compared to those with PTSD who do not, may be at greater risk for a number of problems, including  suicidal thoughts, suicide attempts,  and greater overall distress. Its important for everyone with PTSD and their loved ones to know the risk factors and warning signs of suicide. Treatment Is Critical If you or a loved one who had PTSD is experiencing psychotic symptoms, its very important to seek out treatment. Positive psychotic symptoms can usually be effectively managed through medication.  Addressing PTSD symptoms in treatment may also result in a reduction of psychotic symptoms.

Saturday, May 23, 2020

The Success Of Henry Ford - 1451 Words

â€Å"Coming together is a beginning; keeping together is progress; working together is success.† -Henry Ford. This quote was one of the key ideas that led him to success. Henry Ford went from working on his family s farm to mass manufacturing cars. Early on Henry Ford realized his goal in life, he has countless achievements, and has a forever lasting legacy. To begin, Ford had an interesting childhood. On July 30, 1863, on the Ford family farm, an innovator was born. He got his education in a one room schoolhouse, there he showed early signs of mechanical engineering. In the schoolhouse, he learned how to read, write, spell, and simple arithmetics. However, outside of school, he taught himself to take apart and put together again every†¦show more content†¦He was part of two car companies before the Ford Motor Company. He left both companies, even his own Henry Ford Company, because he was always micromanaged. A great quote from Henry Ford to prove this is â€Å"qua lity means doing it right when no one is looking† This explains that he needed to focus more on innovating the car, and less on pleasing other people during this process. All of these values and traits helped Ford up the path to success. Furthermore, Henry Ford had a lot of achievements and failures while on his way to success. He participated in numerous affairs including: racing cars, creating companies, and innovating cars. While at the Edison Illuminating Company, Ford had a nice home for his family which included a shed. In his shed, he created his first car called the quadricycle. It was simply two bikes with an engine and it could go 60 miles without breaking down. However Henry had a new dream, to make and drive race cars. He wanted to focus on this so he sold the quadricycle and he quit his job. Some time later, he finally entered a race, but as a rookie nobody took him seriously. To everyone’s surprise, Ford came in first place and won a thousand dollars. Thi s victory brought him new investors. Thus Ford created the Henry Ford Company. This company was a huge risk for the investors so, they had inspectors that constantly wanted to know what Ford was up to. Naturally, he hated this kind of poking and heShow MoreRelated Henry Ford Essay1744 Words   |  7 PagesHenry Ford Henry Ford was one of the most brilliant entrepreneurs in creating the automobile assembly line, it was his controversial characteristics and unorthodox approach towards administrating the Ford Motor Company which resulted in the conglomeration of one of the most successful corporations in the world. At the turn of the century everything was booming! The growth of the economy and stock market increased the job opportunities as well as morals. As a result of this industrial revolutionRead MoreBiography of Henry Food757 Words   |  3 PagesHenry Ford is the man who forever changed American automobiles. Henry Ford converted the automobile from a luxury toy to a mainstream item of American society. During the beginning of the 20th century, the automobile was considered a luxury for the wealthy but Ford was determined to create an affordable and reliable car that a majority of Americans could invest in. This model that Henry Ford created was called the Model T, and it is one of the main reasons why Henry Ford is remembered as an extremelyRead MoreHenry Ford And The American Civil War1194 Words   |  5 PagesHenry Ford had only a modest education. He didn’t invent the gasoline engine; he didn’t invent the auto mobile; he didn’t really invent anything. Yet, when he died in 1947, Ford, and the company he founded had a profound effect on the world he taught to drive. 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The work of Henry Ford made a lasting impact on America in regards to both transportation and manufacturing. Henry Ford was much like other children growing up. Ford was born on July 30, 1863 in Dearborn, Michigan. He was raised on a farm and others could tell he would be extremely successful in his future. In order to learn more about the engines and be more successful, Henry Ford built friendships with the men who ran the full-sized steam enginesRead MoreHenry Ford and the Model T Ford789 Words   |  3 Pagesthe Model T ford by Henry Ford. Hitting it off with the entire nation, The Model T Ford was a smashing success. People would say that when the farm was under Henrys control. They would not see any tools. Henry ran his farm the way of the â€Å"future†. Henry ran a very efficient farm however this was not what he wanted to do with life. As we already know Henry wanted to create the first car. Ford was raised on a small farm ran by his father outside of Detroit (Mitchell,1). As a child Henry was very interestedRead MoreThe Flivver King: Henry Ford1571 Words   |  7 Pagesï » ¿The Flivver King: A Story of Ford America In the early 1900’s Henry Ford developed the idea of â€Å"a wagon that will run without a horse†.1 This idea and Ford’s success changed America and its people forever. The development of the automobile played a tremendous role in the economy, labor unions and society. Generally, when most people think of Henry Ford they reflect upon his wealth and contributions to the transportation industry as an infinitely positive phenomenon. It is thought that asideRead MoreEssay on Henry Ford1366 Words   |  6 Pagestruly something special. Once a far fetched dream is now what many people believe to be the back bone of the American economy. When people think about the automobile the name that comes to mind is most usually Henry Ford. 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Henry Ford had a different vision, he saw the potential that the automobile market held, if, he could create an automobileRead MoreHenry Ford : The World s Most Influential Leader1659 Words   |  7 Pagesplethora of leaders, Henry Ford was by far one of the most influential. Mr. Ford played a major role in the history of America from boycotting the great war to enhancing the assembly line, and modern transportation technology. Henry Ford was the world’s most influential leader. From founding one of the worlds most successful car companies, to having a major influence on WWI, he has profoundly shaped the 20th century and left an impact on every single one of our lives. Although Mr. Ford is considered

Tuesday, May 12, 2020

Presume vs. Assume Choosing the Correct Word

Among their other definitions, presume and assume both mean to suppose. However, the two terms suggest different levels of confidence, so they arent interchangeable. Heres how to use these words correctly. How to Use Presume Presume means to suppose, to take for granted, or to take something on (such as a dare or an attitude). The word stems from a Latin verb meaning to take upon oneself, to take liberty, or to take for granted. When presume is used to mean â€Å"to suppose,† the implication is that the supposition is believed to be true based upon proof of evidence or probability. While it does not imply that the supposition is necessarily correct, it does suggest that the speaker (the person doing the presuming) has based their view on available proof. One interesting usage of presume is the familiar legal phrase â€Å"presumed innocent until proven guilty.† Even though there is no evidence of an individuals innocence, the court system intentionally presumes their innocence at the beginning of a trial. In other words, the trial begins with the confidently-held belief that the defendant is innocent. Consequently, the burden of proof falls on the prosecution to demonstrate the defendants guilt. How to Use Assume Assume means to suppose, to take for granted, or to take something on (such as a role). This definition overlaps significantly with that of presume, but there are some meaningful distinctions. When assume is used to mean to take something on, it refers to taking on a new responsibility, a task, or a role. For instance, you might assume a false identity, or assume the position of club secretary. When assume is used to mean â€Å"to suppose,† the implication is that the speaker does not have reason or evidence to back up their assumption. Examples Peter sent his friend a letter three weeks ago, but still hasnt received a response. He assumed that the letter got lost in the mail. Peter has no evidence to back up his belief that the letter was lost in the mail; thus, he is making an assumption. Sally heard a knock on the door. I presume thats Mr. Jones, she said. I invited him over for dinner this evening. Sally is confident in her statement. She invited Mr. Jones over for dinner, so she has solid evidence that he is the person knocking on her door. Sarah is a vegan, so I presume she wont want any of this cheese pizza. In this sentence, the speaker is using evidence to make an educated guess that Sarah will not want pizza based on previous knowledge of her diet, Abraham Lincoln assumed the position of president on March 4, 1861. Here, assume is used to indicate that the subject of the sentence is taking on a new role. How to Remember the Difference   Struggling to remember when to use each word? Keep in mind that presume and proof start with the same two letters. To presume something is to suppose that it is true based on proof (or the belief that there is proof), whereas assumptions are not based upon any evidence or proof.

Wednesday, May 6, 2020

Role Play Exercise Free Essays

Scenarios – Assume that Asian is a new hired outdoor sales executive for company Lennox Design which provide one stop solution for T-shirt and Uniforms supply. We get an Introduction from our existing customer who name Ms Eng that her friend Ms Learn factory have a sports day event by next two month. Now Asian had appointment with the purchases In-charge person Ms Elm, try to approach her to purchases our product to her event uniform. We will write a custom essay sample on Role Play Exercise or any similar topic only for you Order Now Asian:† Hi Ms Limit, I am Asian from Lennox Design, nice to meet you (Handing business card and a company prepared free gift t-shirt to Ms Limit), You friend Ms Eng introducing me that you are interested to order t-shirt for your company sports day event by the next two month. † Ms Limit:† Hello Mr. Asian, nice to meet you too (opening the t-shirt plastic) Woo, nice design for this t-shirt, it is free to me? Asian:† Yup, this t- shirt special deserve to you for free and this t-shirt is design from my company, you may see the quality for our product too. † Ms Limit:† Thanks you, I like it very much. Well, we haven’t made decision for the t-shirt use at the day of events, but we had no much Idea for choosing the new t-shirt, any suggestion Mr.. Asian? † Asian:† Yes, May I now how many pieces t-shirt and the budget for per pieces t-shirt you wish to order in this activity? Ms Elm:† Meme†¦ Elf consider the previous events experience, we need around 500-600 pieces red color plain t-shirt with my company logo and my company have enhance the budget for this events to have a better benefit to our staff, we were set the T-shirt budget in ARMY per pieces. Asian, you are welcome. Here is the deposit ROOM ( pass the money to Asian ), and can I know when can get my t-shirt? † Asian:† Well, normally after confirm the artwork, mass production will take reworking days to process the order. Please do not hesitate to call me if Ms Limit have question for the t-shirt and souvenir, we are the company which specialist in supply souvenir and t-shirt, I wish that you company can give me more chance to serve you in the future. † Ms Limit:† Mr.. Asian, you are modest and see you. (shake hand with Asian) Asian:† See you Ms Limit, Bye. â€Å" How to cite Role Play Exercise, Papers

Saturday, May 2, 2020

Huckleberry Finn by Mark Twain is a true American Essay Example For Students

Huckleberry Finn by Mark Twain is a true American Essay classic. Twain weaves a tremendous story about a boy, Huck, and a slave, Jim, who together overcome obstacles, and eventully reach their goals. Huck is boy who was made for the frointer, where he grows up. He is verypractical, and has superb common sense, allowing him to think situations through, and decide on the best path to choose. Yet Hucks best quality is his deep caring for other human beings, and this is what makes him such a classic american character. Huck will stop at nothing to help other people, as shown in his aiding the king and the duke from escaping the posse, who wanted to kill them, and of his bringing Jim from slavery. Huck helps so many others despite leading a dreadful home life. Huck is forced to fake his own death, and run off from Jim, in order to escape his drunk and disorderly father. Jim is the other major character of this novel. He is a slave who is befriended by Huck, and with Hucks help, he escapes slavery. Huck shows his givingness to others in his aid ing Jim, and together they become inseperable friends, and show that despite drastic differences amongst people, everyone is human, and deserves to be treated equal.